Which blood thinner combo best prevents a second stroke?

NCT ID NCT06591377

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study compares two antiplatelet drug combinations—ticagrelor plus aspirin versus cilostazol plus aspirin—given within 24 hours of a minor stroke or TIA. The goal is to see which combination better prevents new strokes over 90 days while keeping bleeding complications low. About 900 adults aged 18-75 with a first-time large-vessel minor stroke or TIA are being enrolled.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ticagrelor and cilostazol, each combined with aspirin

What this could lead to

If successful, this could identify a better dual-antiplatelet regimen to reduce the risk of another stroke after a minor stroke or TIA.

What could go wrong

This is a single-center trial, and results may not apply to all populations. Both drug combinations increase bleeding risk, which could outweigh benefits.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ischemic stroke large artery stroke transient ischemic attack

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • El-sahel teaching hospital

    RECRUITING

    Cairo, 22514, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Kafr Elsheikh University Hospital

    RECRUITING

    Kafr ash Shaykh, 33511, Egypt

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact