Which blood thinner combo best prevents a second stroke?

NCT ID NCT06591377

Recruiting now Disease control Sponsor: Kafrelsheikh University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study compares two antiplatelet drug combinations—ticagrelor plus aspirin versus cilostazol plus aspirin—given within 24 hours of a minor stroke or TIA. The goal is to see which combination better prevents new strokes over 90 days while keeping bleeding complications low. About 900 adults aged 18-75 with a first-time large-vessel minor stroke or TIA are being enrolled.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ticagrelor and cilostazol, each combined with aspirin
What this could lead to: If successful, this could identify a better dual-antiplatelet regimen to reduce the risk of another stroke after a minor stroke or TIA.
What could go wrong: This is a single-center trial, and results may not apply to all populations. Both drug combinations increase bleeding risk, which could outweigh benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ischemic stroke large artery stroke transient ischemic attack

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ISCHEMIC STROKE

Contacts and locations

Locations

El-sahel teaching hospital
RECRUITING

Cairo, 22514, Egypt
Kafr Elsheikh University Hospital
RECRUITING

Kafr ash Shaykh, 33511, Egypt

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