Monthly shot may keep schizophrenia symptoms at bay

NCT ID NCT00706654

Completed Disease control Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a once-monthly injection of aripiprazole can help people with schizophrenia avoid a relapse of symptoms. Over 900 adults took part, first switching to oral aripiprazole, then receiving either the long-acting shot or another treatment for up to 38 weeks. The main goal was to see how many people experienced worsening symptoms or needed hospitalization.

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Conditions

The condition(s) this trial relates to.

schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SCHIZOPHRENIA

Contacts and locations

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Locations

Study site

Cerritos, California, 90703, United States
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Escondido, California, 92025, United States
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Garden Grove, California, 92845, United States
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Oceanside, California, 92056, United States
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Orange, California, 92868-3298, United States
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Orange, California, 92868, United States
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Pasadena, California, 91106, United States
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Pico Rivera, California, 90660, United States
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San Diego, California, 92102, United States
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San Diego, California, 92103-8620, United States
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San Diego, California, 92123, United States
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Torrance, California, 90502, United States
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Washington D.C., District of Columbia, 20016, United States
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Gainesville, Florida, 32608, United States
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Kissimmee, Florida, 34741, United States
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Plantation, Florida, 33317, United States
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Tampa, Florida, 33613, United States
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Chicago, Illinois, 60612, United States
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Oak Brook, Illinois, 60523, United States
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Shreveport, Louisiana, 71104, United States
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Towson, Maryland, 21286, United States
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Kansas City, Missouri, 64108, United States
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Buffalo, New York, 14213, United States
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New York, New York, 10003, United States
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New York, New York, 10035, United States
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Rochester, New York, 14624, United States
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Hickory, North Carolina, 28601, United States
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South Carolina, North Carolina, 29425, United States
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Garfield Heights, Ohio, 44125, United States
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Toledo, Ohio, 43609, United States
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Oklahoma City, Oklahoma, 73112, United States
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Charleston, South Carolina, 29401, United States
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Charleston, South Carolina, 29407, United States
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Johnson City, Tennessee, 37614-1707, United States
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Nashville, Tennessee, 37212, United States
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Arlington, Texas, 76011, United States
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Austin, Texas, 78756, United States
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Richmond, Virginia, 23230, United States
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Milwaukee, Wisconsin, 53226, United States
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Innsbruck, A-6020, Austria
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Bruges, 8200, Belgium
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Burgas, 8000, Bulgaria
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Pazardzhik, 4400, Bulgaria
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Pleven, 5800, Bulgaria
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Plovdiv, 4000, Bulgaria
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Sofia, 1113, Bulgaria
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Sofia, 1431, Bulgaria
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Sofia, 1632, Bulgaria
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Varna, 9000, Bulgaria
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Santiago, 7500710, Chile
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Santiago, 7510041, Chile
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Santiago, 7510186, Chile
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Santiago, 8053095, Chile
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Santiago, 8330838, Chile
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Santiago, 8900085, Chile
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Temuco, 4781151, Chile
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Valdivia, 5090145, Chile
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Zagreb, 10 090, Croatia
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Zagreb, 10000, Croatia
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Jämejala, Viljandimaa, 71024, Estonia
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Meegomäe, 65526, Estonia
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Tallinn, 10613, Estonia
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Tallinn, 13419, Estonia
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Tartu, 50406, Estonia
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Tartu, 50417, Estonia
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Bully-les-Mines, 62160, France
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Élancourt, 78990, France
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Rennes, 35703, France
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Saint-Nazaire, 44606, France
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Baja, 6500, Hungary
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Balassagyarmat, 2660, Hungary
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Cegléd, 2700, Hungary
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Győőor, 9024, Hungary
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Milan, 20142, Italy
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Milan, 20157, Italy
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Pisa, 56126, Italy
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Bełchatów, 97-400, Poland
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Bialystok, 15-879, Poland
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Bydgoszcz, 85-096, Poland
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Choroszcz, 16-070, Poland
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Krakow, 31-501, Poland
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Leszno, 64-100, Poland
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Pruszków, 05-802, Poland
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Sosnowiec, 41-200, Poland
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Wroclaw, 50-227, Poland
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San Juan, 00918, Puerto Rico
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Pretoria, Gauteng, 0001, South Africa
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Cape Town, Western Province, 7530, South Africa
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Busan, 614-735, South Korea
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Daejeon, 301-721, South Korea
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Gwangju, 501-757, South Korea
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Incheon, 400-711, South Korea
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Seoul, 110-744, South Korea
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Seoul, 137-701, South Korea
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Seoul, 150-950, South Korea
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Muang, Chiangmai, 50100, Thailand
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Muang, Chiangmai, 50200, Thailand
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Bangkok, 10330, Thailand