New surgery could save the areola even when nipple cancer is found

NCT ID NCT07544134

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new surgical approach for women with early breast cancer who need a nipple-sparing mastectomy. If cancer is found in the nipple during surgery, doctors will remove the nipple but try to save the pigmented skin around it (the areola) and rebuild a new nipple right away. The goal is to see if this is safe and leads to better-looking results and higher satisfaction. About 40-60 women will be followed for 3 years to check for cancer return and complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Areola-preserving nipple-sparing mastectomy with immediate nipple reconstruction (surgical procedure)

What this could lead to

If successful, this could offer women a way to keep a more natural-looking breast after mastectomy, even when cancer is found in the nipple, improving self-image and quality of life.

What could go wrong

This is a very early, small pilot study with only 40-60 patients, so results may not apply to everyone. There is a risk of cancer returning in the preserved areola or complications like infection or tissue death.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm ductal breast carcinoma in situ invasive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Second Affiliated Hospital of Zhejiang University School of Medicine

    Hangzhou, Zhejiang, 310009, China