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New surgery could save the areola even when nipple cancer is found

NCT ID NCT07544134

Not yet recruiting Symptom relief Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new surgical approach for women with early breast cancer who need a nipple-sparing mastectomy. If cancer is found in the nipple during surgery, doctors will remove the nipple but try to save the pigmented skin around it (the areola) and rebuild a new nipple right away. The goal is to see if this is safe and leads to better-looking results and higher satisfaction. About 40-60 women will be followed for 3 years to check for cancer return and complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Areola-preserving nipple-sparing mastectomy with immediate nipple reconstruction (surgical procedure)
What this could lead to
If successful, this could offer women a way to keep a more natural-looking breast after mastectomy, even when cancer is found in the nipple, improving self-image and quality of life.
What could go wrong
This is a very early, small pilot study with only 40-60 patients, so results may not apply to everyone. There is a risk of cancer returning in the preserved areola or complications like infection or tissue death.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm ductal breast carcinoma in situ invasive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER DUCTAL CARCINOMA IN SITU, DCIS INVASIVE BREAST CARCINOMA

Contacts and locations

Locations

  • The Second Affiliated Hospital of Zhejiang University School of Medicine

    Hangzhou, Zhejiang, 310009, China

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