New hope for kids with aggressive brain cancer: early trial tests novel immune therapy
NCT ID NCT03389802
Summary
This early-stage study is testing a new antibody drug called APX005M in children and young adults with brain tumors that have come back or are not responding to treatment, or with a newly diagnosed aggressive brain stem glioma. The main goal is to find the safest dose and understand the side effects. The drug is designed to activate the body's immune system to potentially fight the cancer cells.
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Contacts and locations
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Locations
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Baylor College of Medicine
Houston, Texas, 77030, United States
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Children Hospital of Pittsburgh of UPMC
Pittsburgh, Pennsylvania, 15224, United States
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Children's Healthcare of Atlanta
Atlanta, Georgia, 30322, United States
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Children's Hospital Los Angeles
Los Angeles, California, 90026, United States
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Childrens National Medical Center
Washington D.C., District of Columbia, 20010-2970, United States
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Cincinnati Children Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Lucile Packard Children Hospital Stanford University
Palo Alto, California, 94304, United States
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Lurie Childrens Hospital-Chicago
Chicago, Illinois, 60614, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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St. Jude Children Research Hospital
Memphis, Tennessee, 38105, United States
Conditions
Explore the condition pages connected to this study.