4,000 ICU patients join quest to unravel deadly lung and blood infections

NCT ID NCT06521502

Recruiting now Knowledge-focused Sponsor: Vanderbilt University Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study is enrolling 4,000 adults in intensive care with ARDS, sepsis, or pneumonia. Researchers will collect blood, urine, and swab samples, plus track recovery for up to a year. The goal is to identify different patient subtypes and find clues that could lead to better treatments in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help identify biomarkers and risk factors that improve diagnosis and treatment for ARDS, sepsis, and pneumonia.
What could go wrong: This is an observational study, not a treatment trial. It will not directly test any new drug or therapy, so benefits for patients are indirect and long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute respiratory distress syndrome adult acute respiratory distress syndrome Critical Illness infectious disease with sepsis pneumonia Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARDS PNEUMONIA SEPSIS

Contacts and locations

Locations

Denver Health and Hospital Authority
RECRUITING

Denver, Colorado, 80204, United States
Duke University
RECRUITING

Durham, North Carolina, 27710, United States
Fresno Community Hospital and Medical Center
RECRUITING

Fresno, California, 93721, United States
Intermountain Medical Center
RECRUITING

Murray, Utah, 84107, United States
Johns Hopkins Univeristy
RECRUITING

Baltimore, Maryland, 21218, United States
Meharry Medical College
RECRUITING

Nashville, Tennessee, 37208, United States
National Jewish Health
RECRUITING

Denver, Colorado, 80206, United States
Northwestern Memorial Hospital
RECRUITING

Chicago, Illinois, 60611, United States
San Francisco General Hospital
RECRUITING

San Francisco, California, 94110, United States
Stanford University
RECRUITING

Palo Alto, California, 94305, United States
UC Health Medical Center of the Rockies
RECRUITING

Loveland, Colorado, 80538, United States
University of California, San Francisco
RECRUITING

San Francisco, California, 94143, United States
University of Chicago
RECRUITING

Chicago, Illinois, 60637, United States
University of Cincinnati
RECRUITING

Cincinnati, Ohio, 45219, United States
University of Colorado, Denver
RECRUITING

Denver, Colorado, 80045, United States
University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109, United States
University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
University of Utah
RECRUITING

Salt Lake City, Utah, 84132, United States
Vanderbilt University Medical Center
RECRUITING

Nashville, Tennessee, 37232, United States
Washington University School of Medicine
RECRUITING

St Louis, Missouri, 63110, United States

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