Parkinson's pump trial aims to keep Early-Stage patients on their feet

NCT ID NCT02864004

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether an apomorphine pump can improve quality of life for people in the early stages of Parkinson's disease who have just started experiencing motor complications. 134 adults aged 65 or younger with mild Parkinson's used either the pump plus standard care or standard care alone for 12 months. The goal was to see if the pump helps maintain daily function and social participation better than pills alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

apomorphine

What this could lead to

If it works, this could offer a way to manage motor symptoms earlier in Parkinson's, helping people stay active and independent longer.

What could go wrong

This is a Phase 3 trial, but it's relatively small (134 people) and focuses on early-stage patients, so results may not apply to everyone. The pump requires a continuous infusion, which can cause side effects like nausea or skin reactions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • APHM, hospital of Timone

    Marseille, 13385, France

  • Amiens University Hospital

    Amiens, 80054, France

  • Bayonne Côte Basque Hospital

    Bayonne, 64109, France

  • Caen University Hospital

    Caen, 14033, France

  • Caremeau University Hospital

    Nîmes, 30029, France

  • Clermont-Ferrand University Hospital

    Clermont-Ferrand, 63003, France

  • Clinique Beau-Soleil

    Montpellier, 34070, France

  • Hautepierre University Hospital

    Strasbourg, 67098, France

  • Laennec Hospital

    Nantes, 44093, France

  • Lille University Hospital

    Lille, 59037, France

  • Montpellier University Hospital

    Montpellier, 34295, France

  • Nancy University Hospital

    Nancy, 54035, France

  • Pasteur 2 University Hospital

    Nice, 06002, France

  • Pellegrin University Hospital

    Bordeaux, 33000, France

  • Pierre Wertheimer Hospital

    Bron, 69677, France

  • Pitié-Salpêtriere Hospital

    Paris, 75651, France

  • Poitiers University Hospital

    Poitiers, 86021, France

  • Purpan University Hospital

    Toulouse, 31059, France

  • Rennes University Hospital

    Rennes, 35033, France

  • Saint-Etienne University Hospital

    Saint-Etienne, 42055, France