Parkinson's pump trial aims to keep Early-Stage patients on their feet

NCT ID NCT02864004

Completed Symptom relief Sponsor: Rennes University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether an apomorphine pump can improve quality of life for people in the early stages of Parkinson's disease who have just started experiencing motor complications. 134 adults aged 65 or younger with mild Parkinson's used either the pump plus standard care or standard care alone for 12 months. The goal was to see if the pump helps maintain daily function and social participation better than pills alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: apomorphine
What this could lead to: If it works, this could offer a way to manage motor symptoms earlier in Parkinson's, helping people stay active and independent longer.
What could go wrong: This is a Phase 3 trial, but it's relatively small (134 people) and focuses on early-stage patients, so results may not apply to everyone. The pump requires a continuous infusion, which can cause side effects like nausea or skin reactions.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PARKINSON'S DISEASE

Contacts and locations

Locations

APHM, hospital of Timone

Marseille, 13385, France
Amiens University Hospital

Amiens, 80054, France
Bayonne Côte Basque Hospital

Bayonne, 64109, France
Caen University Hospital

Caen, 14033, France
Caremeau University Hospital

Nîmes, 30029, France
Clermont-Ferrand University Hospital

Clermont-Ferrand, 63003, France
Clinique Beau-Soleil

Montpellier, 34070, France
Hautepierre University Hospital

Strasbourg, 67098, France
Laennec Hospital

Nantes, 44093, France
Lille University Hospital

Lille, 59037, France
Montpellier University Hospital

Montpellier, 34295, France
Nancy University Hospital

Nancy, 54035, France
Pasteur 2 University Hospital

Nice, 06002, France
Pellegrin University Hospital

Bordeaux, 33000, France
Pierre Wertheimer Hospital

Bron, 69677, France
Pitié-Salpêtriere Hospital

Paris, 75651, France
Poitiers University Hospital

Poitiers, 86021, France
Purpan University Hospital

Toulouse, 31059, France
Rennes University Hospital

Rennes, 35033, France
Saint-Etienne University Hospital

Saint-Etienne, 42055, France

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