New pill shows promise for tough blood cancers
NCT ID NCT05147467
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new drug called APG-2575 in people whose chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) has come back or stopped responding to other treatments. About 75 adults will take the drug alone to see if it can shrink tumors and control the disease. The goal is to find a new option for patients who have run out of effective therapies.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hainan General Hospital
NOT_YET_RECRUITINGHaikou, Hainan, 570311, China
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Henan Cancer Hospital
RECRUITINGZhengzhou, Henan, 450003, China
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Institute of blood transfusion of Chinese Academy of Medical Sciences
NOT_YET_RECRUITINGTianjin, Tianjin Municipality, 215127, China
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Nanfang Hospital of Southern Medical University
RECRUITINGGuangzhou, Guangdong, 510515, China
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People's hospital of Jiangsu Province
NOT_YET_RECRUITINGSuzhou, Jiangsu, China
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Sun Yat-sen University Cancer Center
RECRUITINGGuangzhou, Guangdong, 510060, China
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The First Affilated Hospital of Nanchang University
NOT_YET_RECRUITINGNanchang, Jiangxi, 330006, China
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The First Affilated Hospital of Soochow University
NOT_YET_RECRUITINGSuzhou, Jiangsu, 215006, China
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The First Affiliated Hospital of Zhejiang University School of Medicine
NOT_YET_RECRUITINGHanzhou, Zhejiang, 310003, China
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Union Hospital medical college Huazhong University of Science and Technology
RECRUITINGWuhan, Hubei, 430022, China
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Zhujiang Hospital of Southern Medical University
NOT_YET_RECRUITINGGuangzhou, Guangdong, 510280, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a Low-Dose antifungal shield vulnerable patients from deadly fungal infections?
- Can a gentler chemo prep make stem cell transplants safer for blood cancer patients?
- Can a Three-Drug combo outsmart High-Risk CLL?
- Can a gentler dose of zanubrutinib keep CLL at bay in the very elderly?
- Can a Two-Drug combo wipe out hidden leukemia cells?
- Can a Chemo-Free pill combo outsmart leukemia at first diagnosis?