New cocktail of four drugs shows promise for tough prostate cancer

NCT ID NCT02913196

First seen May 08, 2026 · Last updated May 09, 2026 · Updated 1 time

Summary

This early-phase study tested a combination of four drugs (apalutamide, abiraterone, docetaxel, and prednisone) in 16 men with metastatic castrate-resistant prostate cancer that had stopped responding to hormone therapy. The main goal was to find a safe dose of apalutamide when given with the other three drugs. Researchers also tracked changes in PSA levels and tumor growth. The study was completed, but results are not yet widely available.

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Contacts and locations

Locations

  • GU Research Network/Urology Cancer Center

    Omaha, Nebraska, 68130, United States

  • Weill Cornell Medical College

    New York, New York, 10065, United States

Conditions

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