Are IBD drugs safe in pregnancy? large french study investigates
NCT ID NCT03134508
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study analyzed data from over 8,700 pregnant women with inflammatory bowel disease (Crohn's or ulcerative colitis) to see how well doctors follow guidelines when prescribing antiTNFα drugs and whether the benefits outweigh the risks for both mother and baby. Researchers looked at complications related to the disease, treatment, and pregnancy, as well as infections in babies during their first year. The goal is to provide clearer evidence for safer treatment decisions during pregnancy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- antiTNFα (anti-tumor necrosis factor alpha) drugs
- What this could lead to
- If successful, this could help doctors make safer decisions about using antiTNFα drugs during pregnancy in women with inflammatory bowel disease.
- What could go wrong
- This is an observational study using existing hospital records, not a controlled trial. It can show associations but cannot prove cause and effect. Results may not apply to other countries or populations.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Chu de Dijon
Dijon, France
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