Special stitches aim to stop pancreatic leaks after major surgery

NCT ID NCT07318493

Recruiting now Disease control Sponsor: The Cleveland Clinic Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether using antiseptic-coated sutures instead of standard ones can lower the chance of a pancreatic fistula (a leak of digestive fluid) after a Whipple procedure. About 436 adults scheduled for this surgery will be randomly assigned to receive either the coated or standard stitches. The main goal is to see if the coated sutures reduce fistula rates within 90 days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: triclosan/antiseptic-coated suture
What this could lead to: If it works, this could reduce a common and serious complication after Whipple surgery, potentially shortening hospital stays and improving recovery.
What could go wrong: This is a relatively small, early-stage trial testing a device modification. The benefit may be small or not statistically significant, and results may not apply to all surgical settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PANCREATODUODENECTOMY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PANCREATODUODENECTOMY WHIPPLE PROCEDURE

Contacts and locations

Locations

Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44195, United States
Cleveland Clinic Akron
RECRUITING

Akron, Ohio, 44307, United States
Cleveland Clinic Fairview Hospital
RECRUITING

Fairview, Ohio, 44111, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.