New painkiller may cut opioid use after major pancreatic surgery

NCT ID NCT07423650

First seen Feb 21, 2026 · Last updated May 16, 2026 · Updated 12 times

Summary

This study tests whether a continuous infusion of nefopam, a non-opioid painkiller, can reduce the need for opioids and improve pain control after pancreatoduodenectomy (a major pancreatic surgery). About 93 adults scheduled for this surgery will be randomly assigned to receive nefopam, lidocaine, or epidural analgesia. Researchers will measure opioid use, pain scores, and recovery quality for 48 hours after surgery.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Prof. O. Fodor Regional Institute of Gastroenterology and Hepatology

    RECRUITING

    Cluj-Napoca, Cluj, Romania

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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