Antibiotics before endoscopy: do they prevent infections in liver patients?

NCT ID NCT07616466

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 480 cirrhosis patients who had variceal bleeding and were getting an endoscopy to prevent future bleeding. Half got antibiotics before the procedure, half did not. The goal was to see if antibiotics reduce infections after the procedure. The study is retrospective, meaning it looked back at past records, so it can't prove cause and effect.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ceftriaxone (an antibiotic)
What this could lead to
If it works, this could clarify whether antibiotics are needed before endoscopy to prevent infections in cirrhosis patients.
What could go wrong
This is a retrospective study, not a controlled trial, so results may be less reliable. It also only looks at short-term outcomes.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Second Affiliated Hospital of Zhejiang University School of Medicine

    Hangzhou, China

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