Antibiotics before endoscopy: necessary or not for cirrhosis patients?
NCT ID NCT06437964
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether giving antibiotics before an endoscopic procedure helps prevent fever and rebleeding in people with cirrhosis who have had variceal bleeding before. 226 patients were randomly assigned to receive the antibiotic ceftriaxone or no antibiotics before the procedure. The goal was to see if skipping antibiotics is just as safe (non-inferior) as using them.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ceftriaxone (an antibiotic)
What this could lead to
If successful, this could show that skipping antibiotics before endoscopy is safe for some cirrhosis patients, reducing unnecessary drug use.
What could go wrong
This is a small, completed trial with only 226 participants. Results may not apply to all patients, and skipping antibiotics could raise infection risk.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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The 2nd Affiliated Hospital, School of Medicine, Zhejiang University, China
Hangzhou, China