Antibiotics for UTIs may disrupt gut bacteria, study finds

NCT ID NCT07424989

Completed Knowledge-focused Sponsor: University Hospital, Rouen Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how antibiotics used to treat urinary tract infections (UTIs) affect the bacteria in the gut. Researchers collected stool samples from 61 hospitalized patients before and after antibiotic treatment to see if resistant bacteria increased. The goal was to understand potential side effects of antibiotics on digestive health.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: antibiotics (ceftriaxone, piperacillin/tazobactam, or temocillin)
What this could lead to: If successful, this could help doctors understand how antibiotic treatments for UTIs affect gut bacteria and the spread of antibiotic resistance.
What could go wrong: This is a small, completed observational study that does not test a new treatment. It only measures changes in gut bacteria, so it may not lead to direct clinical changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

urinary tract infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

URINARY TRACT INFECTION(UTI)

Contacts and locations

Locations

CHU de Rouen

Rouen, 76031, France

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