Can extra cleaning with hydrogen peroxide or UV light slash ICU infections?

NCT ID NCT07233837

Recruiting now Disease control Sponsor: Hospital Israelita Albert Einstein Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding hydrogen peroxide fogging or ultraviolet light to regular cleaning can reduce infections in intensive care units. Over 5,000 adult patients in 12 Brazilian ICUs will take part. Each ICU will try all three methods (standard cleaning, cleaning plus hydrogen peroxide, and cleaning plus UV light) in random order to see which works best.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Hydrogen peroxide aerosol and ultraviolet-C light
What this could lead to: If successful, this could provide a simple, effective way to lower infection rates in intensive care units, reducing antibiotic use and improving patient safety.
What could go wrong: This is a pragmatic trial, but previous studies have shown mixed results. The benefit may be small or limited to specific settings, and the extra cleaning steps add time and cost.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Catheter-Related Infections nosocomial infection Pneumonia, Ventilator-Associated urinary tract infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANTIMICROBIAL CATHETER RELATED BLOOD STREAM INFECTIONS INFECTION, HOSPITAL PNEUMONIA ASSOCIATED WITH MECHANICAL VENTILATION URINARY TRACT INFECTION(UTI)

Contacts and locations

Locations

Fundo Municipal de Saúde de Maringá
RECRUITING

Maringá, Paraná, Brazil
Hospital Dr Leo Orsi Bernardes
RECRUITING

Itapetininga, São Paulo, Brazil
Hospital Estadual de Aparecida de Goiânia
RECRUITING

Aparecida de Goiânia, Goiás, Brazil
Hospital Geral de Caxias do Sul
RECRUITING

Caxias do Sul, Rio Grande do Sul, Brazil
Hospital Maternidade Sao Vicente De Paulo
RECRUITING

Barbalha, Ceará, Brazil
Hospital Pelópidas Silveira
RECRUITING

Recife, Brazil
Hospital Universitário Onofre Lopes
RECRUITING

Natal, Rio Grande do Norte, Brazil
Hospital Universitário da Universidade Federal do Piauí
RECRUITING

Teresina, Piauí, Brazil
Hospital da Restauração
RECRUITING

Recife, Pernambuco, Brazil
Hospital de Pronto Socorro de Porto Alegre
RECRUITING

Porto Alegre, Rio Grande do Sul, Brazil
Instituto Hospital de Base
RECRUITING

Brasília, Federal District, Brazil
Santa Casa de Misericórdia de Passos
RECRUITING

Passos, Minas Gerais, Brazil

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