Engineered immune cells take aim at Hard-to-Treat cancers

NCT ID NCT03745326

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 23 times

Summary

This early-phase trial tested a new treatment for people with advanced cancers (like pancreatic, stomach, or colon cancer) that have a specific genetic change called KRAS G12D. Doctors took participants' own white blood cells, modified them in a lab to better recognize and attack cancer cells, and then infused them back. The goal was to see if this approach is safe and can shrink tumors. Only 5 people took part, and the study is now complete.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.