Could a Plant-Derived drug improve blood flow in septic shock?

NCT ID NCT07657702

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study will test a drug called anisodamine in 20 adults with septic shock who are on a ventilator. The goal is to see if the drug can improve blood flow in small blood vessels and help with a phenomenon called 'vascular waterfall.' This is a very early study to gather information for future, larger trials.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Anisodamine (a drug given intravenously)

What this could lead to

If this works, it could point toward a new way to improve blood flow in septic shock patients, potentially leading to better treatments.

What could go wrong

This is a very small, early pilot study with only 20 patients and no comparison group. It is designed to gather preliminary data, not to prove effectiveness. The drug may not show clear benefits or could have side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Arrhythmias, Cardiac Critical Illness hemophilia B infectious disease with sepsis Sepsis toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College)

    Wuhu, Anhui, 241000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••