Which blade is best? large trial tests emergency intubation tools

NCT ID NCT07223762

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial compares two types of video laryngoscope blades—hyperangulated and standard geometry—in critically ill adults who need a breathing tube in the emergency department or intensive care unit. About 2,500 participants will be randomly assigned to one blade type. The main goal is to see which blade leads to successful tube placement on the first try, with a secondary focus on preventing low oxygen levels during the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

video laryngoscope blade (hyperangulated or standard geometry)

What this could lead to

If it works, this could help doctors choose the best tool for placing breathing tubes in emergency situations, potentially improving success rates and reducing complications.

What could go wrong

This is a device comparison study, not a new drug or cure. Results may not apply to all patients or settings, and the study is not blinded, which could introduce bias.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute respiratory failure Critical Illness

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Baylor Scott & White Research Institute

    Dallas, Texas, 75201, United States

  • Denver Health Medical Center

    Denver, Colorado, 80204, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Hennepin Healthcare component - Hennepin County Medical Center

    Minneapolis, Minnesota, 55415, United States

  • Lahey Clinic, Inc

    Burlington, Massachusetts, 01805, United States

  • Ochsner Clinic Foundation

    Jefferson, Louisiana, 70121, United States

  • Oregon Health & Science University

    Portland, Oregon, 97239, United States

  • Our Lady of the Lake Hospital, Inc.

    Baton Rouge, Louisiana, 70808, United States

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • Stanford University

    Stanford, California, 94305, United States

  • The Ohio State University

    Columbus, Ohio, 43210, United States

  • University of California, Los Angeles

    Los Angeles, California, 90095, United States

  • University of Colorado, Denver Anschutz Medical Campus

    Denver, Colorado, 80045, United States

  • University of Maryland Baltimore

    Baltimore, Maryland, 21201, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina, 27109, United States