Which blade is best? large trial tests emergency intubation tools
NCT ID NCT07223762
First seen Jun 26, 2026 · Last updated Jul 10, 2026 · Updated 3 times
Summary
This trial compares two types of video laryngoscope blades—hyperangulated and standard geometry—in critically ill adults who need a breathing tube in the emergency department or intensive care unit. About 2,500 participants will be randomly assigned to one blade type. The main goal is to see which blade leads to successful tube placement on the first try, with a secondary focus on preventing low oxygen levels during the procedure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- video laryngoscope blade (hyperangulated or standard geometry)
- What this could lead to
- If it works, this could help doctors choose the best tool for placing breathing tubes in emergency situations, potentially improving success rates and reducing complications.
- What could go wrong
- This is a device comparison study, not a new drug or cure. Results may not apply to all patients or settings, and the study is not blinded, which could introduce bias.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Baylor Scott & White Research Institute
Dallas, Texas, 75201, United States
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Denver Health Medical Center
Denver, Colorado, 80204, United States
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Duke University Medical Center
Durham, North Carolina, 27710, United States
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Hennepin Healthcare component - Hennepin County Medical Center
Minneapolis, Minnesota, 55415, United States
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Lahey Clinic, Inc
Burlington, Massachusetts, 01805, United States
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Lsu/Umcno
New Orleans, Louisiana, 70112, United States
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Ochsner Clinic Foundation
Jefferson, Louisiana, 70121, United States
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Oregon Health & Science University
Portland, Oregon, 97239, United States
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Our Lady of the Lake Hospital, Inc.
Baton Rouge, Louisiana, 70808, United States
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Rush University Medical Center
Chicago, Illinois, 60612, United States
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Sentara Norfolk General
Norfolk, Virginia, 23507, United States
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Stanford University
Stanford, California, 94305, United States
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The Ohio State University
Columbus, Ohio, 43210, United States
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University of California, Los Angeles
Los Angeles, California, 90095, United States
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University of Colorado, Denver Anschutz Medical Campus
Denver, Colorado, 80045, United States
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University of Maryland Baltimore
Baltimore, Maryland, 21201, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
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Wake Forest University Health Sciences
Winston-Salem, North Carolina, 27109, United States
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