Heart study asks: is a second look inside arteries worth it?

NCT ID NCT04604197

Ongoing Knowledge-focused Sponsor: Fundación EPIC Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study follows 400 people who had a stent placed in the left main coronary artery. Half get a routine angiogram 6 months later, while the other half have only clinical follow-up. Researchers want to see if the extra imaging reduces the chance of death, heart attack, or stroke over 3 years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could show that routine angiographic follow-up after left main coronary stenting improves long-term outcomes, potentially changing standard care.

What could go wrong

This is an observational study, not a randomized trial, so results may not prove cause and effect. The benefit of extra imaging may be small or outweighed by risks of the procedure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder Coronary Disease Coronary Occlusion coronary stenosis coronary thrombosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY ARTERY DISEASE CORONARY ARTERY STENOSIS CORONARY DISEASE CORONARY OCCLUSION LEFT MAIN CORONARY ARTERY DISEASE

Contacts and locations

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Locations

Hospital Clinico Universitario Lozano Blesa

Zaragoza, 50009, Spain
Hospital Clinico Universitario de Valencia

Valencia, 46010, Spain
Hospital Clinico Universitario de Valladolid

Valladolid, 47003, Spain
Hospital Clínico Universitario de Santiago de Compostela

Santiago de Compostela, 15706, Spain
Hospital Del Mar

Barcelona, 08003, Spain
Hospital Galdakao-Usansolo

Galdakao, Vizcaya, 48960, Spain
Hospital General Juan Ramón Jiménez

Huelva, 21005, Spain
Hospital General Universitario de Albacete

Albacete, 02006, Spain
Hospital General Universitario de Alicante

Alicante, 03010, Spain
Hospital Universitari Bellvitge

Barcelona, 08907, Spain
Hospital Universitari Germans Trias I Pujol

Badalona, Barcelona, 08916, Spain
Hospital Universitari Vall D'Hebron

Barcelona, 08035, Spain
Hospital Universitario 12 de Octubre

Madrid, 28041, Spain
Hospital Universitario Donostia

Donostia / San Sebastian, Gipuzkoa, 20014, Spain
Hospital Universitario La Paz

Madrid, 28046, Spain
Hospital Universitario La Princesa

Madrid, 28006, Spain
Hospital Universitario Lucus Agusti

Lugo, 27003, Spain
Hospital Universitario Marques de Valdecilla

Santander, 39008, Spain
Hospital Universitario Miguel Servet

Zaragoza, 50009, Spain
Hospital Universitario Ramon Y Cajal

Madrid, 28034, Spain
Hospital Universitario Regional de Malaga

Málaga, Malaga, 29010, Spain
Hospital Universitario Reina Sofia

Córdoba, 14004, Spain
Hospital Universitario San Juan de Alicante

Alicante, Spain
Hospital Universitario Virgen Arrixaca

Murcia, 30120, Spain
Hospital Universitario Virgen de Las Nieves

Granada, 18014, Spain
Hospital Universitario de A Coruña

A Coruña, 15006, Spain
Hospital Universitario de Cabueñes

Gijón, 33394, Spain
Hospital Universitario de Ciudad Real

Ciudad Real, 13005, Spain
Hospital Universitario de Cruces

Barakaldo, Bizkaia, 48903, Spain
Hospital Universitario de León

León, 24071, Spain