Blood test may prevent unnecessary early deliveries in preeclampsia
NCT ID NCT07193680
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether a blood test that measures certain markers (sFlt-1/PlGF) can help doctors decide when to deliver babies in women with mild preeclampsia at term. Instead of automatically inducing labor at 37 weeks, women with normal test results would wait until 39 weeks. The goal is to reduce unnecessary inductions without increasing health risks for mothers or babies. The trial will enroll 750 women and compare outcomes between the test-guided group and standard care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- sFlt-1/PlGF ratio test
- What this could lead to
- If successful, this could lead to a more personalized approach to managing preeclampsia, reducing unnecessary early deliveries and their complications.
- What could go wrong
- This is an early-stage trial with a composite outcome, so results may not be definitive. The test may not reliably distinguish who can safely wait, and the study is open-label, which could introduce bias.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Consorci Sanitari de Terrassa
RECRUITINGTerrassa, Spain
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Hospital Clínico Universitario Virgen de la Arrixaca
RECRUITINGMurcia, Spain
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Hospital General Universitari Dr. Balmis
RECRUITINGAlicante, Spain
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Hospital General Universitario de Elche
RECRUITINGElche, Spain
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Hospital Materno Infantil de Gran Canaria
RECRUITINGLas Palmas de Gran Canaria, Spain
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Hospital Universitari Arnau de Vilanova
RECRUITINGLleida, Spain
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Hospital Universitari Dexeus
RECRUITINGBarcelona, BARCELONA, 08024, Spain
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Hospital Universitari MútuaTerrassa
RECRUITINGTerrassa, Spain
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Hospital Universitari Son Espases
RECRUITINGPalma de Mallorca, Spain
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Hospital Universitari de Girona Doctor Josep Trueta
RECRUITINGGirona, Spain
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Hospital Universitari de Tarragona Joan XXIII
RECRUITINGTarragona, Spain
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Hospital Universitario Lozano Blesa
RECRUITINGZaragoza, Spain
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Hospital Universitario Puerta del Mar
RECRUITINGCadiz, Spain
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Hospital Universitario San Cecilio
RECRUITINGGranada, Spain
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Hospital Universitario Virgen Macarena
RECRUITINGSeville, Spain
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Hospital Universitario Virgen de Valme
RECRUITINGSeville, Spain
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Hospital Universitario de A Coruña
RECRUITINGA Coruña, Spain
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Hospital Universitario de Cabueñes
RECRUITINGCabueñes, Spain
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Hospital Universitario de Getafe
RECRUITINGGetafe, Spain
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Hospital Universitario de Jerez
RECRUITINGJerez de la Frontera, Spain
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Hospital Universitario de Torrejón
RECRUITINGTorrejón, Spain
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Hospital universitario 12 de Octubre
RECRUITINGMadrid, Spain
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Vall d'Hebron Hospital Campus
RECRUITINGBarcelona, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can tighter blood pressure control in pregnancy prevent serious complications?
- Could a placental protein unlock the mystery of preeclampsia?
- Tiny particles in the blood may warn of dangerous pregnancy high blood pressure
- Vitamin d may cut risk of repeat preeclampsia in High-Risk pregnancies
- Depression drug may mend blood vessels damaged by preeclampsia
- Postpartum blood pressure control may stop preeclampsia from leading to lifelong hypertension