Can a drug calm long COVID's lung inflammation? new trial aims to find out
NCT ID NCT05926505
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests if the drug anakinra can help people with long COVID who have ongoing breathing issues and signs of an overactive immune system. About 182 adults will receive either anakinra or a placebo for up to 8 weeks. The goal is to see if the drug improves lung function, reduces lung scarring, and prevents hospital visits.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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2nd Department of Propedeutic Medicine, ATTIKON University General Hospital
RECRUITINGChaïdári, Attica, 12462, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••
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4th Department of Internal Medicine, ATTIKON University General Hospital
RECRUITINGChaïdári, Attica, 12462, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Department of Internal Medicine, Hospital of Jesolo, Italy
NOT_YET_RECRUITINGJesolo, Italy
Contact
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Department of Pulmonary Medicine, Barcelona University Hospital
NOT_YET_RECRUITINGBarcelona, Spain
Contact
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Dipartimento Scienze di Laboratorio e Infettivologiche - Fondazione Policlinico Gemelli IRCCS, Roma Italy
NOT_YET_RECRUITINGRome, Italy
Contact
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ID Respiratory Unit, Spallanzani Institute of Rome, Italy
NOT_YET_RECRUITINGRome, Italy
Contact
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Infectious Diseases Clinic, Ospedale Policlinico San Martino IRCCS and Department of Health Sciences, University of Genova, Genoa, Italy
NOT_YET_RECRUITINGGenova, Italy
Contact
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Infectious Diseases Clinic, University of Modena, Italy
NOT_YET_RECRUITINGModena, Italy
Contact
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Out-patient long-COVID department I, Sotiria Athens Hospital of Chest Diseases
RECRUITINGAthens, Attica, 11527, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Out-patient long-COVID department I, Thriasio General Hospital of Elefsina
RECRUITINGMagoula, 19600, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Out-patient long-COVID department II, Sotiria Athens Hospital of Chest Diseases
RECRUITINGAthens, Attica, 11527, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Out-patient long-COVID department II, Thriasio General Hospital of Elefsina
RECRUITINGMagoula, 196 00, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Out-patient long-COVID department III, Evangelismos Athens General Hospital
NOT_YET_RECRUITINGAthens, Attica, 10676, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Out-patient long-COVID department IV, Sotiria Athens Hospital of Chest Diseases
RECRUITINGAthens, Attica, 11527, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Out-patient long-COVID department X, Sotiria Athens Hospital of Chest Diseases
RECRUITINGAthens, 115 27, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Out-patient long-COVID department, AHEPA Hospital of Thessaloniki
RECRUITINGThessaloniki, 54636, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Out-patient long-COVID department, Alexandroupolis University General Hospital
RECRUITINGAlexandroupoli, 68100, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Out-patient long-COVID department, Ioannina University General Hospital
RECRUITINGIoannina, Ioannina, 455 00, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Out-patient long-COVID department, Jena University Hospital
NOT_YET_RECRUITINGJena, Germany
Contact
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Out-patient long-COVID department, Laiko General Hospital
RECRUITINGAthens, Attica, 11527, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Out-patient long-COVID department, Patras University General Hospital
RECRUITINGPátrai, Achaia, 26504, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Out-patient long-COVID department, Tzaneion Piraeus General Hospital
RECRUITINGPiraeus, Piraeus, 18536, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Out-patient long-COVID department, University Hospital of Larissa
NOT_YET_RECRUITINGLarissa, 41110, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS Ospedale San Raffaele & Vita-Salute San Raffaele University, Milan, Italy
NOT_YET_RECRUITINGMilan, Italy
Contact