New SPECT method could reveal hidden heart issues in amyloidosis patients

NCT ID NCT05103943

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at 50 people with TTR amyloid cardiomyopathy, a condition where abnormal proteins build up in the heart. Researchers want to see if a special SPECT scan can measure blood flow in the heart's tiny vessels, which may be impaired even without blocked arteries. Participants will have two scans 24 months apart to track changes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors better understand and monitor heart blood flow problems in TTR amyloidosis patients using widely available SPECT technology.

What could go wrong

This is a small observational study (50 people) with no treatment being tested. It only measures blood flow, so it won't directly improve patient outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Amyloid Neuropathies, Familial restrictive cardiomyopathy wild type ATTR amyloidosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHRU de TOURS

    Tours, France

  • CHU Caen

    Caen, 14033, France

  • CHU Orleans

    Orléans, 45067, France

  • CHU d'ANGERS

    Angers, France