Headache trigger test: could amylin be the culprit?
NCT ID NCT07340775
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study gives people with persistent post-traumatic headache a hormone called amylin (or a placebo) to see if it triggers migraine-like headaches. The goal is to understand why headaches continue after a mild brain injury. Only 21 adults will take part, and the results may help design future treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- pramlintide (amylin analogue)
- What this could lead to
- If it works, this could help explain why some people get headaches after a head injury, pointing toward new treatment targets.
- What could go wrong
- This is a very small, early-phase study (21 people) that only looks at headache triggers, not treatment. Results may not apply to everyone with post-traumatic headache.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Rigshospitalet Glostrup
Glostrup Municipality, 2600, Denmark
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