Heart surgery patients may get a patch to stop dangerous rhythm problems

NCT ID NCT06722196

Recruiting now Prevention Sponsor: Jilin Heart Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether placing a biodegradable patch soaked with the drug amiodarone on the heart during surgery can prevent atrial fibrillation (a common irregular heartbeat) afterward. About 500 adults having elective heart surgery will be randomly assigned to get either the amiodarone patch or a plain saline patch. The goal is to see if the drug patch reduces the number of patients who develop atrial fibrillation while in the hospital.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: amiodarone
What this could lead to: If it works, this could provide a simple, targeted way to prevent dangerous heart rhythm problems after cardiac surgery, reducing complications and hospital stays.
What could go wrong: This is still an early-phase trial with 500 participants, so results may not apply to all patients. The patch could cause side effects like inflammation or bleeding, and it may not reduce AF as hoped.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION (AF)

Contacts and locations

Locations

Jilin Heart Hospital
RECRUITING

Changchun, Jinlin, 130000, China

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