Can amino acids shield kidneys after heart surgery in kids?

NCT ID NCT07212595

Recruiting now Disease control Sponsor: Dana Fuhrman Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This study tests whether giving children an amino acid infusion during and after heart surgery can lower their risk of acute kidney injury and reduce time on a ventilator. About 30 children at high risk will receive either the amino acid or a placebo for up to 72 hours. The goal is to see if this simple nutritional supplement can protect kidney function and speed recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Amino acid infusion (Trophamine 10%)
What this could lead to: If it works, this could point toward a simple, safe way to protect children's kidneys after heart surgery and reduce time on breathing machines.
What could go wrong: This is a small early-phase trial with only 30 children, so results may not be conclusive. The amino acid infusion may not reduce kidney injury or ventilator time compared to placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute kidney injury prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE KIDNEY INJURY MECHANICAL VENTILATION

Contacts and locations

Locations

Cincinnati Children's Hospital Medical Center
RECRUITING

Cincinnati, Ohio, 45229, United States

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