Experimental cancer drug study halted early

NCT ID NCT04117958

First seen Oct 31, 2025 · Last updated May 15, 2026 · Updated 27 times

Summary

This early-stage study tested a new drug called AMG 199 in adults with advanced stomach, esophageal, colorectal, or pancreatic cancers that have a specific marker (MUC17). The main goals were to check safety and find the right dose. The study was stopped early, so results are limited.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MUC17-POSITIVE SOLID TUMORS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Aichi Cancer Center

    Nagoya, Aichi-ken, 464-8681, Japan

  • Amsterdam UMC - location VUmc

    Amsterdam, 1081 HV, Netherlands

  • Asan Medical Center

    Seoul, 138-736, South Korea

  • City of Hope National Medical Center

    Duarte, California, 91010, United States

  • Hospital Clinico Universitario de Valencia

    Valencia, Valencia, 46010, Spain

  • Hospital Universitari Vall d Hebron

    Barcelona, Catalonia, 08035, Spain

  • Institut Gustave Roussy

    Villejuif, 94805, France

  • Klinikum der Universitaet Muenchen Campus Grosshadern

    München, 81377, Germany

  • Klinikum rechts der Isar

    München, 81675, Germany

  • Landeskrankenhaus Salzburg

    Salzburg, 5020, Austria

  • Leids Universitair Medisch Centrum

    Leiden, 2333 ZA, Netherlands

  • National Cancer Center Hospital

    Chuo-ku, Tokyo, 104-0045, Japan

  • National Cancer Center Hospital East

    Kashiwa-shi, Chiba, 277-8577, Japan

  • National Taiwan University Hospital

    Taipei, 10002, Taiwan

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • Severance Hospital Yonsei University Health System

    Seoul, 03722, South Korea

  • Taipei Veterans General Hospital

    Taipei, 11217, Taiwan

  • Universitaetsklinikum Hamburg Eppendorf Onkologisches Zentrum

    Hamburg, 20246, Germany

  • Universitaetsklinikum Leipzig

    Leipzig, 04103, Germany

  • University of California at Irvine Medical Center

    Orange, California, 92868, United States

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina, 27157, United States

Conditions

Explore the condition pages connected to this study.