Experimental cancer drug AMG 199 tested in patients with stomach, colon, and pancreatic tumors

NCT ID NCT04117958

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tested an experimental drug called AMG 199 in adults with advanced stomach, gastroesophageal junction, colorectal, or pancreatic cancers that have a specific protein (MUC17). The main goals were to check safety and find the best dose. The study was stopped early, so results are limited.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for COLORECTAL CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm gastric adenocarcinoma gastric neoplasm gastroesophageal junction adenocarcinoma pancreatic ductal adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aichi Cancer Center

    Nagoya, Aichi-ken, 464-8681, Japan

  • Amsterdam UMC - location VUmc

    Amsterdam, 1081 HV, Netherlands

  • Asan Medical Center

    Seoul, 138-736, South Korea

  • City of Hope National Medical Center

    Duarte, California, 91010, United States

  • Hospital Clinico Universitario de Valencia

    Valencia, Valencia, 46010, Spain

  • Hospital Universitari Vall d Hebron

    Barcelona, Catalonia, 08035, Spain

  • Institut Gustave Roussy

    Villejuif, 94805, France

  • Klinikum der Universitaet Muenchen Campus Grosshadern

    München, 81377, Germany

  • Klinikum rechts der Isar

    München, 81675, Germany

  • Landeskrankenhaus Salzburg

    Salzburg, 5020, Austria

  • Leids Universitair Medisch Centrum

    Leiden, 2333 ZA, Netherlands

  • National Cancer Center Hospital

    Chuo-ku, Tokyo, 104-0045, Japan

  • National Cancer Center Hospital East

    Kashiwa-shi, Chiba, 277-8577, Japan

  • National Taiwan University Hospital

    Taipei, 10002, Taiwan

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • Severance Hospital Yonsei University Health System

    Seoul, 03722, South Korea

  • Taipei Veterans General Hospital

    Taipei, 11217, Taiwan

  • Universitaetsklinikum Hamburg Eppendorf Onkologisches Zentrum

    Hamburg, 20246, Germany

  • Universitaetsklinikum Leipzig

    Leipzig, 04103, Germany

  • University of California at Irvine Medical Center

    Orange, California, 92868, United States

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina, 27157, United States