Experimental CAR t therapy targets Hard-to-Treat lung cancer

NCT ID NCT03392064

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase study tests a new treatment called AMG 119 for adults with small cell lung cancer that has returned or not responded to standard chemotherapy. The treatment uses specially engineered immune cells (CAR T cells) designed to find and attack cancer cells. The main goals are to check safety and find the right dose, while also looking at whether the treatment can shrink tumors or slow the disease.

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Conditions

The condition(s) this trial relates to.

small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Site

    Tampa, Florida, 33612, United States

  • Research Site

    Houston, Texas, 77030, United States