Could stem cells slow ALS? new trial results are in

NCT ID NCT04745299

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 3 trial tested a stem cell treatment called Lenzumestrocel in 123 people with ALS. The treatment uses the patient's own bone marrow stem cells and is given alongside the standard drug Riluzole. The goal was to see if it could slow the disease and improve survival and function. Results are being analyzed to determine if this approach offers real benefits.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Lenzumestrocel (stem cells from the patient's own bone marrow)

What this could lead to

If it works, this could slow the progression of ALS and help patients maintain function longer.

What could go wrong

This is a single Phase 3 trial with 123 participants. Results may not apply to everyone, and stem cell treatments carry risks like infection or immune reactions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

amyotrophic lateral sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hanyang university hospital

    Seoul, Seoul, 04763, South Korea

  • Korea University Anam Hospital

    Seoul, 02841, South Korea

  • Pusan National University Yangsan Hospital

    Yangsan, Kyungsangnam-do, 50612, South Korea

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Seoul National University Hospital

    Seoul, South Korea