ALS walking troubles linked to brain changes, study finds

NCT ID NCT01874808

Completed Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how ALS affects the way people start walking and keep their balance. Researchers will compare ALS patients with and without balance issues, plus healthy volunteers, using walking tests and brain scans. The goal is to find out if certain brain changes cause walking problems in ALS. About 59 people will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors better understand why some ALS patients have trouble with balance and walking, potentially guiding future treatments.
What could go wrong: This is an observational study, not a treatment trial. It is small (59 people) and only looks at brain and movement patterns, so it won't directly lead to a new therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

amyotrophic lateral sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AMYOTROPHIC LATERAL SCLEROSIS

Contacts and locations

Locations

Hôpital Pitié-Salpétrière, Département des Maladies du Système Nerveux 47-83 Boulevard de l'Hôpital

Paris, 75013, France

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