Can a simple pill ease stent discomfort? new trial tests two options

NCT ID NCT06966804

Recruiting now Symptom relief Sponsor: Penang Hospital, Malaysia Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 24, 2026 · Updated 2 times

Summary

This study tests whether two common blood pressure drugs, terazosin and tamsulosin, can reduce urinary symptoms like pain and urgency after a ureteral stent is placed. 150 adults in Malaysia will be randomly assigned to take one of the drugs or receive standard care for 14 days. Researchers will track symptom scores and painkiller use to see which approach works best.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Terazosin and Tamsulosin (alpha-blocker drugs)
What this could lead to: If successful, this could show that a short course of an alpha-blocker drug reduces uncomfortable urinary symptoms after stent placement, improving patient comfort.
What could go wrong: This is a moderate-sized trial (150 people) comparing two drugs to no drug, so results may not apply to all patients. Side effects from the drugs are possible, and the benefit may be small.

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Conditions

The condition(s) this trial relates to.

nephrolithiasis ureterolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

STENT RELATED SYMPTOMS

Contacts and locations

Locations

Hospital Pulau Pinang
RECRUITING

George Town, Pulau Pinang, 10450, Malaysia
Sultanah Bahiyah Hospital, Alor Setar
RECRUITING

Alor Star, Kedah, 05460, Malaysia

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