Can a higher dose slow lung damage in Alpha-1 patients?

NCT ID NCT07326592

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether higher doses of the drug Respreeza/Zemaira can slow lung damage better than the standard dose in adults with emphysema caused by Alpha-1 antitrypsin deficiency. About 270 participants will receive weekly IV infusions for 3 years. The goal is to find the optimal dose to preserve lung function and density.

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