New study seeks better ways to track rare lung disease
NCT ID NCT05297812
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study follows 286 adults with Alpha-1 Antitrypsin Deficiency, a genetic condition that can damage the lungs and liver. Researchers use CT scans and blood tests over three years to see how lung density changes. The goal is to find biological markers that could help design better clinical trials for future treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could identify reliable biomarkers to speed up development of new treatments for Alpha-1 Antitrypsin Deficiency.
What could go wrong
This is an observational study, not testing a treatment. It may not find useful biomarkers, and results may not apply to all patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Boston University
Boston, Massachusetts, 02118, United States
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Columbia University
New York, New York, 10032, United States
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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National Jewish Health
Denver, Colorado, 80206, United States
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University of Alabama at Birmingham
Birmingham, Alabama, 35233, United States
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University of California - Los Angeles
Los Angeles, California, 90095, United States
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University of Chicago
Chicago, Illinois, 60637, United States
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University of North Carolina
Chapel Hill, North Carolina, 27514, United States
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University of Utah
Salt Lake City, Utah, 84108, United States