Gout drug allopurinol may boost heart function in african americans with resistant hypertension
NCT ID NCT05888233
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether allopurinol, a common gout medication, can improve heart function in African American veterans with resistant hypertension. Participants take allopurinol for 8 weeks, and researchers measure changes in heart function, exercise ability, and quality of life. The trial involves 40 people in Birmingham, Alabama.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Allopurinol
What this could lead to
If it works, this could point toward a new way to improve heart function and quality of life for African Americans with resistant hypertension.
What could go wrong
This is a small, early-phase trial with only 40 participants, so results may not apply to everyone. Allopurinol can cause side effects like rash or kidney issues.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Birmingham VA Medical Center, Birmingham, AL
Birmingham, Alabama, 35233-1927, United States