Can your reaction to a drink predict future alcohol problems?

NCT ID NCT00961792

Ongoing Knowledge-focused Sponsor: University of Chicago Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study examines how young adults who regularly binge drink respond to alcohol, caffeine, and Benadryl. Researchers want to see if these responses can predict future drinking patterns. About 800 participants will complete lab sessions and be followed for at least two years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ethanol (alcohol), Diphenhydramine (Benadryl), Caffeine
What this could lead to: If successful, this could help identify early signs of problem drinking and point toward ways to prevent alcohol misuse.
What could go wrong: This is an observational study, not a treatment trial. It only looks at responses and future behavior, so it won't directly lead to a new therapy or cure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

alcohol abuse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALCOHOLISM

Contacts and locations

Locations

Clinical Addictions Research Laboratory

Chicago, Illinois, 60637, United States

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