Can a simple protein infusion prevent deadly Re-Bleeding in cirrhosis patients?

NCT ID NCT07395141

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tests whether adding albumin to standard treatment reduces re-bleeding and death in adults with cirrhosis who have acute variceal bleeding. Sixty participants will be randomly assigned to receive either albumin for three days plus standard care, or standard care alone. The main outcomes are re-bleeding during hospitalization and at six weeks, as well as in-hospital mortality.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Albumin

What this could lead to

If it works, this could show that adding albumin to standard treatment helps prevent re-bleeding and improves survival in people with cirrhosis and acute variceal bleeding.

What could go wrong

This is a small, early-phase trial with only 60 participants, so results may not apply to everyone. Albumin is generally safe, but it may not provide significant benefit over standard care alone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver esophageal varices with bleeding Fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dr Sumit Rungta

    Lucknow, Uttar Pradesh, 206003, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact