New hope for hard-to-treat colorectal cancer? drug combo trial underway

NCT ID NCT05846867

First seen Mar 18, 2026 · Last updated May 14, 2026 · Updated 9 times

Summary

This study tests two experimental drugs, AK119 and AK112, alone or with chemotherapy, in 170 adults with a specific type of colorectal cancer (pMMR/MSS) that often doesn't respond well to standard treatments. The goal is to see if these combinations can shrink tumors or slow the disease. Participants will be monitored for side effects and how long the cancer stays under control.

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Contacts and locations

Locations

  • Cancer Hospital Affiliated to Harbin Medical University

    Harbin, China

Conditions

Explore the condition pages connected to this study.