New drug cocktail aims to shrink Hard-to-Treat breast tumors

NCT ID NCT05227664

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether adding two experimental drugs (AK117 and AK112) to standard chemotherapy can shrink tumors in people with advanced triple-negative breast cancer that hasn't been treated yet. About 120 participants will receive the combination. The main goals are to see how many respond and what side effects occur.

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Conditions

The condition(s) this trial relates to.

triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hunan Cancer Hospital

    Changsha, China

  • Xiangyang Central Hospital

    Xiangyang, China