New pill takes on tough breast cancer in first human trial

NCT ID NCT07581314

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial tests an oral drug called Zn-Telomir in 76 adults with advanced or metastatic triple-negative breast cancer that has worsened after prior treatments. The study has two parts: first, finding a safe dose, and second, checking if the drug shrinks tumors. It is the first time this drug is being tested in humans.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Zn-Telomir (oral capsules that regulate metals and protect telomeres)

What this could lead to

If it works, this could point toward a new oral treatment option for advanced triple-negative breast cancer, a hard-to-treat cancer.

What could go wrong

This is a very early first-in-human trial with only 76 participants, so safety and effectiveness are not yet known. Many early cancer drugs fail to show benefit in larger studies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast neoplasm triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.