Could a breathing trick plus mild zaps strengthen brain pathways in MS?

NCT ID NCT06413602

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at whether combining a special breathing technique (called acute intermittent hypoxia, or AIH) with mild electrical stimulation of leg muscles can boost brain-to-muscle signals in people with relapsing forms of multiple sclerosis. About 40 participants will have their ankle strength and brain responses measured after each type of stimulation, alone and together. The goal is to see if the combination works better than either one alone, which could lead to better rehabilitation therapies in the future.

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Conditions

The condition(s) this trial relates to.

chronic progressive multiple sclerosis Hypoxia multiple sclerosis relapsing-remitting multiple sclerosis secondary progressive multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Shirley Ryan AbilityLab

    Chicago, Illinois, 60611, United States