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Can AI learn to tune spinal cord stimulators?

NCT ID NCT07817238

Knowledge-focused Sponsor: Istanbul Gelisim University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 14, 2026 · Last updated Sep 15, 2026 · Updated 1 time

Summary

Researchers are comparing four large language models, ChatGPT-4o, Claude, Grok 3, and Gemini 2.5 Pro, on how well they recommend electrode contact configurations for epidural electrical stimulation in spinal cord injury. The study uses five standardized synthetic scenarios and no real patients. Experts in spinal cord injury rehabilitation and electrical stimulation will rate each model's responses for clinical accuracy, technical feasibility, safety awareness, consistency with current guidance, and completeness.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
large language model clinical decision support (ChatGPT-4o, Claude, Grok 3, Gemini 2.5 Pro)
What this could lead to
If the models perform well, this could point toward AI tools that help clinicians plan spinal cord stimulation settings more efficiently.
What could go wrong
The study uses only five synthetic scenarios and no real patients, so the results may not reflect how these models handle complex, real-world cases. Expert ratings can also vary between reviewers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

20 people

The number who actually took part.

Started

Sep 2026

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

No human study population is included. The analytical sample consists of five standardized synthetic spinal cord injury scenarios and the responses generated for these scenarios by ChatGPT-4o, Claude, Grok 3, and Gemini 2.5 Pro. Each model is evaluated under the same standardized prompting conditions. Model outputs are anonymized and independently rated by expert evaluators for clinical accuracy, technical feasibility, safety awareness, consistency with clinical guidance, and response completeness.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Responses generated for one of the five predefined standardized synthetic spinal cord injury scenarios. * Responses generated using the identical standardized prompt specified in the study protocol. * Responses generated by one of the four prespecified large language models. * Complete responses available for expert evaluation. Exclusion Criteria: * Responses generated using prompts that differ from the standardized study prompt. * Incomplete, interrupted, or technically corrupted model outputs. * Duplicate responses or outputs not corresponding to a predefined synthetic scenario. * Any response generated using real patient-identifiable or personal health information.

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Conditions

The condition(s) this trial relates to.

spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Spinal cord injury

Contacts and locations

Locations

  • Istanbul Gelisim University

    Istanbul, Istanbul, 34290, Turkey (Türkiye)

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