AI may match depression patients to the right therapy faster

NCT ID NCT06567340

Recruiting now Disease control Sponsor: Rotherham Doncaster and South Humber NHS Foundation Trust Source: ClinicalTrials.gov ↗

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This trial tests whether an artificial intelligence tool called StratCare can improve depression treatment by recommending personalized therapy paths. About 1,250 adults with depression will be split into two groups: one using StratCare to guide treatment choice, the other following standard stepped care. Researchers will track mood and quality of life over 18 months to see if the AI-driven approach leads to better recovery rates.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: StratCare, an AI-driven decision-support tool that recommends personalized depression treatment pathways
What this could lead to: If it works, StratCare could help more people recover from depression by matching them to the right therapy from the start.
What could go wrong: The trial is large but still tests a single AI tool in one healthcare system; results may not apply elsewhere, and the algorithm's recommendations may not suit everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anxiety disorder Depression depressive disorder mood disorder Psychological Well-Being

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSION

Contacts and locations

Locations

Central and Nort h West London NHS Foundation Trust
RECRUITING

London, NW1 3AX, United Kingdom
Cheshire and Wirral Partnership NHS Foundation Trust
RECRUITING

Chester, CH2 1BQ, United Kingdom
Homerton Healthcare NHS Foundation Trust
RECRUITING

London, E9 6SR, United Kingdom
Lancashire and South Cumbria NHS Foundation Trust
RECRUITING

Preston, Lancashire, PR5 6AW, United Kingdom
Rotherham Doncaster and South Humber NHS Foundation Trust
RECRUITING

Doncaster, South Yorkshire, DN4 8QN, United Kingdom
Somerset NHS Foundation Trust
RECRUITING

Taunton, Somerset, TA1 5DA, United Kingdom
Surrey and Borders Partnership NHS Foundation Trust
RECRUITING

Leatherhead, Surrey, KT22 7AD, United Kingdom
Tees, Esk and Wear Valleys NHS Foundation Trust
RECRUITING

Darlington, Durham, DL2 2TS, United Kingdom
Vita Health Group
RECRUITING

Nottingham, Nottinghamshire, United Kingdom
West London NHS Trust
RECRUITING

Southall, London, UB2 4SD, United Kingdom

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