Heart surgery risk for chronically ill patients may be explained by cell aging

NCT ID NCT07389785

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This research program studies why people with multiple long-term conditions like kidney or lung disease are more likely to suffer organ damage after heart surgery. Researchers will analyze existing data from over 3,000 patients to understand how aging-related changes in heart cells increase vulnerability. The goal is to identify potential drug targets that could protect organs during surgery.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this research could identify new drug targets to protect organs during heart surgery, especially for people with multiple long-term conditions.
What could go wrong
This is an observational study using existing data, not a clinical trial testing a treatment. It may not lead to any new therapies, and findings may not apply to all patients.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Leicester

    Leicester, Leicester, LE1 7RH, United Kingdom

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