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Exercise or keto: which better fights Obesity-Linked inflammation?

NCT ID NCT07834099

NEW Disease control Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 22, 2026 · Last updated Sep 22, 2026

Summary

Researchers compare aerobic exercise and a ketogenic diet in 120 obese premenopausal women aged 35 to 50 with a high waist-to-hip ratio. The study measures changes in blood markers tied to inflammation and hormones, including free testosterone, TNF alpha, IL6, and high molecular weight adiponectin, along with BMI and waist-to-hip ratio. Participants follow one of the two approaches under the same assessment conditions to see which has a stronger effect on these obesity-related biomarkers.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
aerobic exercise and a ketogenic diet
What this could lead to
If one approach works better, it could give women and doctors a clearer first choice for lowering obesity-related inflammation and hormone imbalances.
What could go wrong
This is a small, short study in one group of women, so the results may not apply to men, older women, or people with different health conditions. Neither diet nor exercise is easy to stick with, and dropout could weaken the findings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

120 people

The number who actually took part.

Started

Feb 2026

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

35 to 50 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: sedentary obese premenopausal woman aged 35-50 years with a BMI of 30-34.9 and a WHR above 0.85, and with none of the exclusion criteria - Exclusion Criteria: are subjects losing even one of the inclusion criteria or having any health condition that could hinder their ability to exercise or engage in the ketogenic diet protocol. \-

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aerobic exercise Keto diet Obesity (disorder)

Contacts and locations

Locations

  • Faculty of Physical Therapy

    Cairo, 11828, Egypt

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