Exercise as medicine: can a 12-Week program shift breast cancer biomarkers?
NCT ID NCT07798492
First seen Sep 01, 2026 · Last updated Sep 02, 2026 · Updated 1 time
Summary
This trial tests whether a 12-week supervised aerobic exercise program can improve physical function, quality of life, and cognitive function in women who have finished treatment for early-stage breast cancer and are in remission. Researchers will measure blood levels of three biomarkers linked to inflammation and metabolism, along with walking distance and patient-reported outcomes, at the start, at week 6, and at week 12. The goal is to see if regular exercise is associated with beneficial changes in these measures.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- A supervised aerobic exercise program
- What this could lead to
- If it works, this could point toward a simple, drug-free way to improve quality of life and physical function for breast cancer survivors, and possibly reduce inflammation-related biomarkers.
- What could go wrong
- This is a small, early-stage trial with only 20 participants, so results may not apply to all breast cancer survivors. Exercise is generally safe, but some participants may find it hard to stick with the program.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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20 people
The number who actually took part.
- Started
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Jun 2026
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria Women aged 18-65 years. Histologically confirmed stage I-II nonmetastatic breast cancer. Completion of indicated primary cancer treatment at least 6 months before enrollment and currently in remission. Ongoing endocrine therapy was permitted. No participation in regular structured physical activity during the preceding 6 months. Medically eligible to participate in aerobic exercise and study assessments. Physician clearance to participate in aerobic exercise. Residing in or near the city where the study was conducted. Provision of written informed consent. Exclusion Criteria Metastatic breast cancer. Clinically significant cardiovascular, respiratory, neurological, or musculoskeletal conditions that could limit safe participation in aerobic exercise. Clinically significant lymphedema. Pregnancy or breastfeeding. Use within the preceding 8 weeks of antidepressants, anxiolytics, antipsychotics, chronic analgesics, or sedatives considered likely to influence cognitive assessments or biological outcomes.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ankara Yildirim Beyazit University
Ankara, Turkey (Türkiye)
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Gazi University
Ankara, Turkey (Türkiye)
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