Lab-Grown mini tumors could guide pancreatic cancer treatment
NCT ID NCT06813079
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study explores whether growing miniature versions of a patient's own pancreatic tumor in the lab (called organoids) can help doctors choose the most effective drug for that individual. About 25 adults with advanced, inoperable pancreatic cancer will have their tumor organoids tested against two drugs, cobimetinib and ponatinib. The goal is to see if this personalized approach leads to tumor shrinkage or better disease control.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Cobimetinib and Ponatinib
What this could lead to
If successful, this approach could make treatment for advanced pancreatic cancer more personalized and effective, potentially improving survival and quality of life.
What could go wrong
This is a small, early-phase trial (25 participants) testing a new method. The drugs may not work for everyone, and side effects could be significant.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ADVANCED CANCER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Princess Margaret Cancer Centre
RECRUITINGToronto, Ontario, M5G 1M9, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact