Experimental antibody drug tested for Tough-to-Treat leukemia

NCT ID NCT03698552

First seen Nov 03, 2025 · Last updated Jun 10, 2026 · Updated 32 times

Summary

This study tested a drug called ADCT-602 in 37 people with a type of blood cancer (B-cell acute lymphoblastic leukemia) that had returned or stopped responding to other treatments. The drug is a lab-made antibody that targets a protein (CD22) on cancer cells to stop them from growing. The study was stopped early, but it aimed to find the safest dose and see if the drug could shrink or eliminate the cancer.

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Contacts and locations

Locations

  • City of Hope Comprehensive Cancer

    Monrovia, California, 91016, United States

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.