New combo therapy targets Hard-to-Cure leukemia in early trial
NCT ID NCT02879695
First seen May 16, 2026 ยท Last updated May 16, 2026
Summary
This early-stage study tests whether adding immune-boosting drugs (nivolumab and ipilimumab) to blinatumomab can help people with a severe form of B-cell leukemia that has returned or not responded to treatment. The main goals are to find safe doses and understand side effects. About 28 adults with relapsed or refractory B-ALL or mixed phenotype acute leukemia are participating.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ we know it does not capture everything.
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Contacts and locations
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Locations
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah, 84112, United States
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Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland, 21287, United States
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
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University of Kentucky/Markey Cancer Center
Lexington, Kentucky, 40536, United States
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University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, Pennsylvania, 15232, United States
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Yale University
New Haven, Connecticut, 06520, United States
Conditions
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