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New hope for elderly lung cancer patients: targeted pill shows promise

NCT ID NCT05673187

Ongoing Disease control Sponsor: ETOP IBCSG Partners Foundation Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a daily pill called adagrasib in 68 patients with a specific type of advanced lung cancer (KRAS G12C mutation) who are either 70 or older or have poor physical health. The goal is to see if the drug can shrink tumors or stop them from growing. Patients take the medication twice a day until their disease gets worse or side effects become too severe.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KRAS P.G12C NSCLC STAGE IV

Contacts and locations

Locations

  • AULSS2 Marca Trevigiana Treviso

    Treviso, Italy

  • Alicante University Hospital

    Alicante, Spain

  • Beaumont Hospital

    Dublin, Ireland

  • Christie NHS Manchester

    Manchester, United Kingdom

  • Complejo Hospitalario Universitario a Coruña

    A Coruña, Spain

  • Hospital General Universitario de Valencia (University Hospital Valencia)

    Valencia, Spain

  • Hospital Universitario Fundacion Jimenez Diaz

    Madrid, Spain

  • Hospital Universitario Puerta de Hierro

    Madrid, Spain

  • Hospital de Basurto

    Bilbao, Spain

  • Hôpital de Marseille

    Marseille, France

  • ICO Badalona - Hospital Germans Trias i Pujol

    Badalona, Spain

  • ICO Bellvitge -H. Duran i Reynals / H. Bellvitge

    L'Hospitalet de Llobregat, Spain

  • Instiute Jules Bordet

    Brussels, Belgium

  • Istituto Nazionale Tumori "Regina Elena"

    Rome, Italy

  • Le Mans - CHG

    Le Mans, France

  • Santa Maria della Misericordia Hospital

    Perugia, Italy

  • University Hospital Limerick

    Limerick, Ireland

  • University Hospital Waterford

    Waterford, Ireland

More trials for these conditions

Other studies related to the condition(s) this trial covers.