New heart valve trial aims to improve treatment for severe aortic stenosis

NCT ID NCT05847751

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a new heart valve called ACURATE neo2 in 51 patients with severe aortic stenosis, a condition where the heart's main valve is narrowed. The valve is placed using a tube through an artery, avoiding open-heart surgery. Researchers are tracking how many patients survive or have a stroke after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ACURATE neo2 heart valve (transcatheter aortic valve replacement device)

What this could lead to

If successful, this could show that the ACURATE neo2 valve is safe and effective for treating severe aortic stenosis in Middle Eastern patients.

What could go wrong

This is a small, single-arm study with only 51 participants, so results may not apply to all patients. The procedure carries risks like stroke or death.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

aortic valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ain shams Specialized hospital

    Cairo, Egypt

  • American University of Beirut

    Beirut, Lebanon

  • Badr hospital

    Cairo, Egypt

  • King Fahad Armed Forces Hospital

    Jeddah, Saudi Arabia

  • King Fahad National Guard Hospital

    Riyadh, Saudi Arabia

  • Magdy Yacoub heart center

    Aswān, Egypt

  • National Guard Hospital - King Abdulaziz Medical City

    Riyadh, Saudi Arabia