New heart valve trial aims to improve treatment for severe aortic stenosis

NCT ID NCT05847751

Ongoing Disease control Sponsor: Ceric Sàrl Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 24, 2026 · Updated 3 times

Summary

This study is testing a new heart valve called ACURATE neo2 in 51 patients with severe aortic stenosis, a condition where the heart's main valve is narrowed. The valve is placed using a tube through an artery, avoiding open-heart surgery. Researchers are tracking how many patients survive or have a stroke after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ACURATE neo2 heart valve (transcatheter aortic valve replacement device)
What this could lead to: If successful, this could show that the ACURATE neo2 valve is safe and effective for treating severe aortic stenosis in Middle Eastern patients.
What could go wrong: This is a small, single-arm study with only 51 participants, so results may not apply to all patients. The procedure carries risks like stroke or death.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

aortic valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SEVERE AORTIC VALVE STENOSIS

Contacts and locations

Locations

Ain shams Specialized hospital

Cairo, Egypt
American University of Beirut

Beirut, Lebanon
Badr hospital

Cairo, Egypt
King Fahad Armed Forces Hospital

Jeddah, Saudi Arabia
King Fahad National Guard Hospital

Riyadh, Saudi Arabia
Magdy Yacoub heart center

Aswān, Egypt
National Guard Hospital - King Abdulaziz Medical City

Riyadh, Saudi Arabia

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