Can a simple touch or cold pack make shots less painful?

NCT ID NCT07049640

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether acupressure or cold application to acupressure points before a ventrogluteal injection could reduce pain, anxiety, and improve comfort. 102 adults who needed daily penicillin injections took part. Researchers measured pain, anxiety, comfort, and vital signs after each technique.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

acupressure and cold application

What this could lead to

If effective, these simple techniques could offer drug-free ways to ease pain and anxiety during injections.

What could go wrong

This is a small, completed study without a placebo control, so results may not be widely applicable. The effects could be due to natural recovery or attention from staff.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anxiety disorder Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Siirt Training and Research Hospital

    Siirt, Siirt, 47200, Turkey (Türkiye)